all CAPS: A Story of Ice and Fire - Part 2

<p>Things get a little nerdy in this episode, which focuses on the basic science of what makes the inflammasome tick in CAPS, as well as data on the use of interleukin 1 inhibition.<br /> Hint: Listen to “The Inflammasome for Dunces” episode first, and this one will make more sense.</p> Intro :20 Recap of Part 1 :33 Overview of this episode 1:56 Familial cold autoinflammatory syndrome 3:04 Muckle-Wells syndrome 6:34 The two checkpoint problem 8:36 What do we know about the inhibition of the inflammasome? 11:13 Back to the trebuchet analogy 11:48 <p>Brought to you by GSK. Considering a treatment change for patients with active SLE? Learn abou...